Ib pab neeg tshawb fawb los ntawm Mie University hauv Nyij Pooj tau pom tias thaum ntxov zebrafish embryos (embryos ob peb teev tom qab fertilization) tuaj yeem muaj kev nyab xeeb irradiated nrog 278 nm UVC.
UVC- LEDs nyob ib ncig ntawm 260nm yog siv los ua kom tsis muaj menyuam vim lawv ntxias thiab ua kom tsis muaj DNA puas tsuaj los ntawm cov kab mob thiab kab mob. Feem ntau ntawm cov kev tshawb fawb tam sim no tsom rau qhov cuam tshuam ntawm UVC nrog wavelengths qis dua 240nm (207nm, 222nm, 233nm) ntawm kev tua tus kabmob tshiab. Txawm li cas los xij, muaj qee qhov kev tshawb fawb txog kev toxicity, kev nyab xeeb, thiab cov lus teb ntawm cov kab mob mus rau UVC irradiation nyob ib ncig ntawm 280 nm.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Cov txiaj ntsig kev tshawb fawb ntawm cov ntsiab lus no muab kev tshawb fawb txog kev nyab xeeb ntawm UVC-LED siv rau tib neeg lub cev. Nyob rau tib lub sijhawm, pab pawg tshawb fawb pom tias UVC yog qhov tsim nyog rau kev tua kab mob thiab cov kab mob xws li tus mob coronavirus, nrog rau kev tua kab mob hauv dej hiav txwv.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
GMKJ LED thev naus laus zis tau koom nrog kev noj qab haus huv thiab ntse lub teeb ci, muab kev lag luam nrog ntau yam ntawm UVA UVB UVC LED, infrared IR LED VCSEL cov khoom lag luam thiab cov kev daws teeb meem, thiab muaj ntau pua lub siab -cov koom tes zoo hauv tsev thiab txawv teb chaws kev lag luam los koom ua ke txhawb kev siv lub teeb pom kev zoo los tsim kev noj qab haus huv thiab ntse lub neej. ua rau.
