Peb feem ntau hais txog lactic acid thaum lub sijhawm ua haujlwm, thiab peb txhua tus paub tias kev tsim cov lactic acid muaj teeb meem rau lub cev. Yog li kev sib raug zoo ntawm kev tawm dag zog thiab lactic acid yog dab tsi?
Lactic acid (ib qho tshuaj muaj nyob hauv hws) yog ib qho tseem ceeb biomarker kom muaj nuj nqis thaum lub sij hawm qoj ib ce. Nws nyob hauv txoj haujlwm tseem ceeb hauv kev ua haujlwm thiab yog ib txwm ua los ntawm - khoom hauv tib neeg lub cev. Tom qab kev tawm dag zog hnyav, tib neeg tsim cov ntshav ntau dua. Lactic acid.
Piv txwv li: lactate, uas yog tsim thaum lub sij hawm tawg ntawm qabzib nyob rau hauv tsis muaj oxygen nyob rau hauv cov ntaub so ntswg, yog ib tug tseem ceeb biomarker uas muaj nyob rau hauv ob leeg ntshav thiab hws, xav txog kev siv ntawm lub cev kev ua si thiab cov pa oxygenation ntawm cov leeg.
During exercise, energy-requiring muscles quickly run out of oxygen and fall back on an alternate metabolic pathway to provide energy at the "cost" of accumulating lactate, which can cause pain and fatigue.
Cov lactate tom qab ntawd tso rau hauv cov hlab ntsha thiab tshem tawm ib feem los ntawm hws, lub ntsiab lus ntawm cov khoom siv tshuaj lom neeg tuaj yeem ntsuas qhov concentration ntawm lactate hauv hws los qhia kev siv zog los yog cov leeg mob hauv lub sijhawm.
During training, the uncomfortable burning sensation in the muscles is not caused by lactic acid, but by hydrogen ions produced by the pH drop in the body. The fatigue of muscle strength is related to lactic acid, but the cause of discomfort and subsequent residual pain It's more related to acid in the blood, when muscle fatigue usually means acidosis or an increase in the accumulation of lactic acid in the blood.
Lactic acid tsis yog ua rau qaug zog, tab sis nws cuam tshuam nrog kev kawm poob qis, yog li nws tuaj yeem xav tias yog ib feem ntawm biochemical recycling los pab kom qaug zog.
Tsis ntev los no, ntau tus kws tshawb fawb tau txuas ntxiv tshawb fawb txog kev sib raug zoo ntawm kev tawm dag zog thiab lactic acid thiab kev siv cov lactic acid hauv kev cob qhia kev ua kis las, thiab tau ua tiav cov txiaj ntsig zoo. functional status, thiab lwm yam.
Nrog rau kev txhim kho ntxiv ntawm cov khoom siv hnav, qhov muaj peev xwm ntawm tsis yog -invasively siv hws lactate ntsuas thiab txuas ntxiv taug qab nws cov evolution thaum lub sij hawm qoj ib ce, ntxiv rau cov tshuaj ib txwm siv tshuaj colorimetry, zoo nkaus li nyob ze rau peb ntawm kev soj ntsuam cov ntsiab lus lactate.
Recently, ACS (American Chemical Society) published an article - Can Wearable Sweat Lactate Sensors Contribute to Sports Physiology? It's incomplete, but exercise physiologists are investigating whether the technology could improve athletic performance while preventing injuries.
Cov kws tshawb fawb tau hais tias lub hom phiaj ntawm lactate sensor thev naus laus zis yog los saib xyuas cov ntsiab lus lactic acid hauv tib neeg lub cev hauv lub sijhawm tiag tiag thiab txuas mus rau lub xeev ntawm tib neeg kev tawm dag zog, txhawm rau txhawm rau paub meej hauv lub sijhawm tiag tiag txawm tias lub zog siv los ntawm tus neeg ncaws pob yog dhau lawm. loj los yog me me, thiab txhim kho kev cob qhia efficiency. Tam sim no, lub hom phiaj tseem nyob deb. Kuj tseem muaj qhov tsis nkag siab txog kev sib raug zoo ntawm hws thiab ntshav lactate thiab lwm yam biomarkers, vim tias tsis muaj pov thawj txaus rau kev sib raug zoo ntawm kev ua kis las thiab lactate concentrations.
Lactic acid yog ib yam khoom los ntawm- ntsuas los ntawm tus kws tshawb fawb kis las lossis tus kws qhia ua kis las los ntsuas qib kev ua kis las ntawm tus neeg ncaws pob thaum lub sijhawm kuaj lub cev, thiab qhov tseeb - ntsuas lub sij hawm tawm hws lactate, nrog rau lwm cov biomarkers, tso cai Kev cob qhia kev cob qhia kom zoo saib xyuas thiab hloov kho, uas ua kom cov neeg ncaws pob tsis Kev cob qhia nyuaj lossis tsawg dhau, yog li muab cov kev cob qhia raug cai uas ua rau cov neeg ncaws pob ua tau zoo nyob rau lub sijhawm ntev.
Kub thiab pH feem ntau cuam tshuam rau electrochemical nyeem ntawm lactic acid, ua rau kev ntsuas qis dua li qhov xav tau, yog li cov kws tshawb fawb tau tsim ib txoj hauv kev uas siv cov txheej txheem tshwj xeeb tsim los ntawm polymer txheej sab nraum lub sensor kom cais cov lactic acid los ntawm hws.
Lub polymer tiv thaiv cov reactive enzymes nyob rau hauv lub sensor los ntawm reacting nrog rau lwm yam tshaj li lactic acid thiab enables lub sensor nyeem ntau dua cov lactic acid ntau dua li feem ntau nyeem los ntawm electrochemical sensors.
The researchers are currently using the technology for physical tests, where blood and sweat measurements correlate with athletic performance in athletes, and sweat samples are taken to validate the sensor's performance in the lab.
Hauv kev tshawb fawb tsis ntev los no, Tokyo University of Science thiab Technology tau tsim cov mos mos thiab tsis yog -mob microfluidic sensor los ntsuas qhov concentration ntawm lactic acid hauv hws nyob rau lub sijhawm tiag tiag, cov khoom siv hnav uas yuav pab tau thaum lub cev qoj ib ce hnyav lossis saib xyuas. lub xeev ntawm koj lub cev thaum ua haujlwm.
The researchers employed a method called "electron-beam-induced graft polymerization," in which functional molecules are bound to carbon-based materials that can spontaneously bind enzymes.
Cov kws tshawb fawb tau ua cov khoom siv rau hauv cov kua mem kua uas tuaj yeem siv los luam cov electrodes. Qhov kawg yog siv lub tshuab hluav taws xob hloov tau yooj yim los ua kom nws sib haum nrog kev tshuaj ntsuam luam ntawv, txheej txheem sib sib zog nqus uas tuaj yeem ntsuas tau. Tom qab ua tiav cov txheej txheem kev paub, cov kws tshawb fawb tau kawm Cov neeg ua haujlwm tau tsim cov txheej txheem tsim nyog los sau hws thiab xa mus rau cov sensors.
Qhov no yog ua tiav los ntawm micro- tawm hws cov txheej txheem ua los ntawm cov khoom siv polydimethylsiloxane (PDMS), uas suav nrog ntau qhov chaw me me, lub qhov hluav taws xob, thiab lub chamber rau nruab nrab ntawm cov sensors, uas tuaj yeem tiv tauj ncaj qha rau ntawm daim tawv nqaij.
The detection of the sensor and its operating range for lactate concentrations have been determined to be suitable for studying the "lactate threshold," the point in time at which aerobic metabolism changes to anaerobic metabolism during exercise.
Tiag -Lub sij hawm saib xyuas ntawm lub cev tshwm sim yog qhov tseem ceeb rau cov kev siv cuam tshuam xws li tib neeg kev noj qab haus huv thiab kev kho mob, thiab kev saib xyuas cov qib lactate yuav pab txhim kho kev cob qhia cov neeg ncaws pob thiab cov kev tawm dag zog niaj hnub rau kev kho cov neeg mob thiab cov neeg laus, thiab tswj kev nce qib ntawm kev txav mus los.
Cov kws tshawb fawb twb tau sim qhov kev siv ntawm lub sensor nyob rau hauv tiag - ntiaj teb no scenarios, thiab kev nce qib nyob rau hauv qhov kev tshawb fawb no yuav pab txhim kho lub teb ntawm wearable tshuaj sensors uas pab peb zoo taug qab cov txheej txheem ntawm lub cev thiab noj qab nyob zoo.
Many studies have shown that lactate testing can help us clarify and understand the principle of training, regulate and control training intensity, assess and predict training level, so lactate is often called "training ruler".
Lub hws lactate sensor tau lees paub tias yog ib qho kev cog lus los daws qhov kev tsis txaus ntawm feem ntau cov kev kuaj ntshav.
Tam sim no, nrog kev txhim kho txuas ntxiv ntawm lactic acid xeem txoj hauv kev thiab cov qauv ntawm kev txhim kho kev ua haujlwm ntawm kev ua haujlwm hnyav, kev kuaj lactic acid thiab kev ntsuam xyuas yuav siv ntau dua thiab siv dav hauv kev ua kis las.
Ob qhov hloov pauv hloov pauv hloov pauv tau tsim los ntawm lub tuam txhab kev hnov qab yog ua raws li PI thiab PET feem. Siv PI / PET kom hloov tau yooj yim thiab ncab, cov electrodes tuaj yeem haum rau tib neeg cov tawv nqaij thiab tam sim no tau siv dav hauv cov khoom siv hnav. Sensors xws li hws lactate sensing detection.
PI hloov tau yooj yim interdigital electrode yog cov organic polymer zaj duab xis, uas tsis yog tsuas yog resistant rau hydrolysis, kub thiab corrosion, tab sis kuj muaj zoo biocompatibility thiab zoo rwb thaiv tsev.
